valproate adverse effects on creatine metabolism and transport in a patient under drug therapy.
نویسندگان
چکیده
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منابع مشابه
Valproate adverse effects on creatine metabolism and transport in a patient under drug therapy
1 Department of Biology, School of Medicine, Laboratory of Biochemistry, Rabta Hospital, Jebbari, 1007 Tunis, Tunisia 2 Department of Biochemistry, School of Medicine, Molecular Biology and Metabolic Diseases, CHRU, 57039 Lille, France 3 Department of Biochemistry and Molecular Biology, School of Medicine, Laboratory of Biochemistry, Molecular Biology and Metabolic Diseases, CHRU, 57039 Lille, ...
متن کاملDisorders of creatine transport and metabolism.
Creatine is a nitrogen containing compound that serves as an energy shuttle between the mitochondrial sites of ATP production and the cytosol where ATP is utilized. There are two known disorders of creatine synthesis (both transmitted as autosomal recessive traits: arginine: glycine amidinotransferase (AGAT) deficiency; OMIM 602360; and guanidinoacetate methyltransferase (GAMT) deficiency (OMIM...
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ADVERSE EFFECTS (AEs) AND PATIENT BEHAVIORS DURING THE COURSE OF OPIOID THERAPY How Drug Causes AEs
How the Drug Works Pentazocine is an analgesic with agonist/ antagonist action. By competing for the mu receptor in certain circumstances it may act as a mu opioid receptor antagonist and a kappa opioid receptor agonist, which when administered orally is approximately equivalent on a mg-for-mg basis in analgesic effect to codeine. Onset and duration of action and the degree of pain relief are r...
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15 صفحه اولAdverse events in a newborn on valproate therapy due to loss-of-function mutations in CYP2C9
An increased risk of valproate-induced toxicity has been reported in children, particularly in those younger than 2 years of age. Significant variations in valproate pharmacokinetics and shifts in the metabolic pathways towards CYP2C9-dependent metabolism seem to play some role in the age-related differences in the incidence of adverse events. We present the case of a premature patient with mod...
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عنوان ژورنال:
iranian journal of neurologyجلد ۱۳، شماره ۲، صفحات ۱۰۸-۱۰۹
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